Ernesto the most wanted mafia boss and dies in an accident. Ernesto's wife Regina, her mother, her daughter and her sisters-in-law are arrested for accomplices in drug trafficking, but they are all released, except Regina for being the wife of the capo. When Regina is released for not having evidence against her, she continues to manage the businesses that belonged to her husband, becoming her employer. The risks are great, her daughter and sister-in-law are kidnapped and killed by their enemies. Regina and her people will not rest until they avenge her deaths, but in the end the boss will find a big unexpected surprise.