Higanjima is a remote island in Japan. Bloodthirsty vampires dwell on Higanjima as a result of a virus that infected people. Miyamoto Akira who has come to Higanjima in search of his missing older brother, Atsushi, learns of a vaccine that can neutralize the vampires and boldly gets into their midst. However, Atsushi is infected and has become an underling of the master vampire, Miyabi, who rules the island.