Ke Tumi Nandini is the journey of a young, spirited girl Nandini (Rupsha), who is of tom-boyish nature and aspires to be a medical student. She develops a liking for a man named Abir ( Bonny) much older than her and a fitness trainer and social worker . Over the course of the rest of the film, Nandini constantly tries to attract the attention of Abir in different ways possible but he seems to be not interested in her. Will Nandini be able to make Abir fall in love with her? Will her love story have a happy ending?